Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoprotein E (gE).

Title:

Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoprotein E (gE).

Dataset

identifier:	1377501
description:	epitope description:GERLMQPTQMSAQEDLGDDT antigen name:Envelope glycoprotein E host organism:Cavia porcellus Hartley antibody name:guinea pig sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	9178473

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004174
landingPage:	http://www.iedb.org/assay/1377501

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1997

Dimension

study type:	b cell assays
subject species:	Human herpesvirus 3 H-551

Person

fullName:	M Garcia-Valcarcel W J Fowler D R Harper D J Jeffries G T Layton

Data Type

method:	ELISA

Study

name:	Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoprotein E (gE).
description:	In a separate experiment, Freund's complete adjuvant was used. Results yielded a similar pepscan peptide-recognition profile to that of alum as adjuvant.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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