Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoprotein E (gE).

Title:

Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoprotein E (gE).

Dataset

identifier:	1377508
description:	epitope description:RGIDSGERLMQPTQMSAQED antigen name:Envelope glycoprotein E host organism:Cavia porcellus Hartley antibody name:guinea pig sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	9178473

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004174
landingPage:	http://www.iedb.org/assay/1377508

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1997

Dimension

study type:	b cell assays
subject species:	Human herpesvirus 3 H-551

Person

fullName:	M Garcia-Valcarcel W J Fowler D R Harper D J Jeffries G T Layton

Data Type

method:	ELISA

Study

name:	Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoprotein E (gE).
description:	In a separate experiment, using Freund's complete adjuvant in place of alum, all peptides reacted with the antiserum in the pepscan; however, peaks at peptides gE(91-110), gE(101-120), gE(106-125), gE(116-135), gE(131-150), and gE(141-161) were observed.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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