Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1377703 |
| description: |
epitope description:alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc
antigen name:Variant surface glycoprotein (VSG, atypical), putative (UniProt:Q380X5)
host organism:Camelus dromedarius
antibody name:NbAn33
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
16604085 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1003946 |
| landingPage: |
http://www.iedb.org/assay/1377703 |
| type: |
Literature
|
| publicationVenue: |
Nat Med
|
| dates: |
2006
|
| study type: | b cell assays |
| subject species: | Trypanosoma brucei brucei |
| fullName: |
Toya Nath Baral
Stefan Magez
Benoî
t Stijlemans
Katja Conrath
Benoit Vanhollebeke
Etienne Pays
Serge Muyldermans
Patrick De Baetselier
|
| method: |
ELISA
|
| name: |
Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.
|
| description: |
This branched high-mannose oligosaccaride (Man9-GlcNAc2) is expressed at the Variable surface Glycoproteins (VSG) of T. brucei brucei and T. b. rhodesiense.
Recognition of the purified VSG from T. b. brucei AnTat 1.1 is dependent on the presence of N-linked oligomannose as alpha-mannosidase treatment abolishes the recognition. VSGs from T.b. brucei MiTat 1.1, 1.2, 1.4 and 1.5 and from T. b. rhodesiense ETat 1.2 are also recognized.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
