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Title: Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses.
identifier: 1789870
description:
epitope description:S2, T5, E6
antigen name:Matrix protein 2
host organism:Homo sapiens
antibody name:TCN-031, TCN-032
aggregation:
instance of dataset
availability:
available
primaryPublications: 20615945
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1020887
landingPage: http://www.iedb.org/assay/1789870
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2010
study type: b cell assays
subject species: Influenza A virus
fullName:
Andres G Grandea 3rd
Ole A Olsen
Thomas C Cox
Mark Renshaw
Philip W Hammond
Po-Ying Chan-Hui
Jennifer L Mitcham
Witold Cieplak
Shaun M Stewart
Michael L Grantham
Andrew Pekosz
Maki Kiso
Kyoko Shinya
Masato Hatta
Yoshihiro Kawaoka
Matthew Moyle
method:
surface plasmon resonance (SPR)
name:
Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses.
description:
The epitope was deduced.
The Ka for TCN-031 was 1.0 x 106 M-1 * s-1. The Ka for TCN-032 was 7.4 x 105 M-1 * s-1.

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