Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies.

Dataset

identifier:	1789877
description:	epitope description:FAEDVGSNKGAIIGLMVGGVVIA antigen name:Amyloid beta A4 protein host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	20685980

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020946
landingPage:	http://www.iedb.org/assay/1789877

Publication

type:	Literature
publicationVenue:	J Neurosci
dates:	2010

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Heinz Hillen Stefan Barghorn Andreas Striebinger Boris Labkovsky Reinhold Mü ller Volker Nimmrich Marc W Nolte Claudia Perez-Cruz Ingrid van der Auwera Fred van Leuven Marcel van Gaalen Anton Y Bespalov Hans Schoemaker James P Sullivan Ulrich Ebert

Data Type

method:	in vivo assay

Study

name:	Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies.
description:	APP mice passively immunized with the epitope-specific mAb improved their cognitive performance and Tg2576 mice improved their synaptic spine density.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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