Structures of the glycopeptidolipid antigens of Mycobacterium abscessus and Mycobacterium chelonae and possible chemical basis of the serological cross-reactions in the Mycobacterium fortuitum complex.

Title:

Dataset

identifier:	1790518
description:	epitope description:3,4-di-O-methyl-alpha-L-rhamnose antigen name:GPL C-II host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	8025677

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003321
landingPage:	http://www.iedb.org/assay/1790518

Publication

type:	Literature
publicationVenue:	Microbiology
dates:	1994

Dimension

study type:	b cell assays
subject species:	Mycobacterium chelonae

Person

fullName:	L M Ló pez-Marí n N Gautier M A Lané elle G Silve M Daffé

Data Type

method:	ELISA

Study

name:	Structures of the glycopeptidolipid antigens of Mycobacterium abscessus and Mycobacterium chelonae and possible chemical basis of the serological cross-reactions in the Mycobacterium fortuitum complex.
description:	This is 3,4-di-O-methylrhamnosyl moiety of glycopeptidolipid (GPL). It is found in the GPL of Mycobacterium chelonae, M. absessus and M. peregrinum. Epitope was identified by using purified glycopeptidolipid (GLP) with various carbohydrate moieties from M. fortuitum complex (M. abscessus, M. peregrinum and M. chelonae) and by beta-elimination with alkaline borohydride. Antiserum from animals immunized with crude lipid extracts from M. chelonae recognized the epitope in GPLS from M. abscessus and M. peregrinum.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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