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Title: Protective efficacy of group A streptococcal vaccines containing type-specific and conserved M protein epitopes.
identifier: 1791323
description:
epitope description:KQAEDKVKASREAKKQVEKALEQLEDKVK
host organism:Mus musculus ICR
aggregation:
instance of dataset
availability:
available
primaryPublications: 20546830
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1020921
landingPage: http://www.iedb.org/assay/1791323
type:
Literature
publicationVenue:
Vaccine
dates:
2010
study type: b cell assays
subject species:
fullName:
Thomas A Penfound
Edna Y Chiang
Elwaleed A Ahmed
James B Dale
method:
in vivo assay
name:
Protective efficacy of group A streptococcal vaccines containing type-specific and conserved M protein epitopes.
description:
Immunization of mice with the peptide resulted in minimal protection against challenge with group A Streptococcus (GAS) type 6 as determined by LD50. The calculated LD50 in mice that received J14-KLH was 1.46 x 10^5 compared to 5.41 x 10^4 in sham immunized mice.

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