Chimeric vaccine composed of viral peptide and mammalian heat-shock protein 60 peptide protects against West Nile virus challenge.

Title:

Chimeric vaccine composed of viral peptide and mammalian heat-shock protein 60 peptide protects against West Nile virus challenge.

identifier:	1792410
description:	epitope description:LVTVNPFVSVATANS antigen name:Genome polyprotein host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	20331473

study type:	b cell assays
subject species:	West Nile virus

fullName:	Orly Gershoni-Yahalom Shimon Landes Smadar Kleiman-Shoval David Ben-Nathan Michal Kam Bat-El Lachmi Yevgeny Khinich Michael Simanov Itzhak Samina Anat Eitan Irun R Cohen Bracha Rager-Zisman Angel Porgador

method:	in vivo assay

name:	Chimeric vaccine composed of viral peptide and mammalian heat-shock protein 60 peptide protects against West Nile virus challenge.
description:	Mice immunized with the epitope conjugated to HSP carrier peptide were protected from WNV challenge. Mice immunized with the epitope alone were not as well protected. Immunized mice also had lower viral titer than non-immunized mice.

name:	iedb
homePage:	http://www.iedb.org

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