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Title: Shigella flexneri O-antigen epitopes: chemical and immunochemical analyses reveal that epitopes of type III and group 6 antigens are identical.
identifier: 1766908
description:
epitope description:2-O-acetyl-alpha-L-rhamnose
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:MASF 6-1
aggregation:
instance of dataset
availability:
available
primaryPublications: 2424840
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1000663
landingPage: http://www.iedb.org/assay/1766908
type:
Literature
publicationVenue:
Infect Immun
dates:
1986
study type: b cell assays
subject species: Shigella flexneri
fullName:
N I Carlin
A A Lindberg
method:
ELISA
name:
Shigella flexneri O-antigen epitopes: chemical and immunochemical analyses reveal that epitopes of type III and group 6 antigens are identical.
description:
This determinant, known as O antigen 6, is part of the O-PS of S. flexneri of several serotypes, such as 1b, 3a, 3b and 4b.
Removing of O-acetyl groups from LPS completely abolished the epitope-specific mAb binding in ELISA suggesting O-acetyl group as a essential component of epitope. Similar result was observed in passive hemagglutination assay.

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