Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001560 |
| landingPage: |
http://www.iedb.org/assay/1767164 |
| type: |
Literature
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| publicationVenue: |
Proc Natl Acad Sci U S A
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| dates: |
2004
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Frederic A Fellouse
Christian Wiesmann
Sachdev S Sidhu
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| method: |
surface plasmon resonance (SPR)
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| name: |
Synthetic antibodies from a four-amino-acid code: a dominant role for tyrosine in antigen recognition.
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| description: |
Epitope residues were calculated from the structure [PDB: 1TZI] as antigen residues interacting with the Fab at atomic distance of 4 Å
. Mapping between residue numbers in PDB and external identifier was done as provided in PDB.
Epitope specific Fab YADS 2, which bound with high affinity to human VEGF, also exhibited appreciable affinity for the homologous (90% amino acid identity) mouse VEGF.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
