Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis. Secondary role of iodination.

Title:

Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis. Secondary role of iodination.

identifier:	1767295
description:	epitope description:STDDYASFSRAL + SCM(Y5) antigen name:Thyroglobulin host organism:Mus musculus CBA/J
aggregation:	instance of dataset
availability:	available
primaryPublications:	7499874

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Y C Kong D J McCormick Q Wan R W Motte B E Fuller A A Giraldo C S David

method:	ELISA

name:	Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis. Secondary role of iodination.
description:	The tyrosine at position 5 was substituted with L-thyronine (T0) or L-thyroxine (T4). Mice immunized with mouseTg did not produce antibodies to the epitope containing thyronine (0) or thyroxine (T4).

name:	iedb
homePage:	http://www.iedb.org

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