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Title: Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis. Secondary role of iodination.
identifier: 1767301
description:
epitope description:STDDYASFSRAL + SCM(Y5)
antigen name:Thyroglobulin
host organism:Mus musculus CBA/J
aggregation:
instance of dataset
availability:
available
primaryPublications: 7499874
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007129
landingPage: http://www.iedb.org/assay/1767301
type:
Literature
publicationVenue:
J Immunol
dates:
1995
study type: b cell assays
subject species: Homo sapiens
fullName:
Y C Kong
D J McCormick
Q Wan
R W Motte
B E Fuller
A A Giraldo
C S David
method:
ELISA
name:
Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis. Secondary role of iodination.
description:
The tyrosine at position 5 was substituted with L-thyronine (T0) or L-thyroxine (T4).
Mice immunized with the epitope containing thyronine (0) or thyroxine (T4) produced antibodies that recognized both T0 and T4 epitope.

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