A V H H that neutralizes the zinc metalloproteinase activity of botulinum neurotoxin type A. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

A V H H that neutralizes the zinc metalloproteinase activity of botulinum neurotoxin type A.

Dataset

identifier:	1767320
description:	epitope description:DQPPTSRVPSLR host organism:Camelus dromedarius antibody name:VHH17
aggregation:	instance of dataset
availability:	available
primaryPublications:	20093370

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019113
landingPage:	http://www.iedb.org/assay/1767320

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	2010

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Jeeraphong Thanongsaksrikul Potjanee Srimanote Santi Maneewatch Kiattawee Choowongkomon Pramuan Tapchaisri Sou-ichi Makino Hisao Kurazono Wanpen Chaicumpa

Data Type

method:	biological activity

Study

name:	A V H H that neutralizes the zinc metalloproteinase activity of botulinum neurotoxin type A.
description:	Epitope (mimotope) specific VHH is shown to specifically inhibit the light chain of botulinum toxin A in its peptidase activity on human SNAP25 protein or on peptide 187-203 of SNAP25, which is a cleavage motif of BoTxA.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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