Antibody response against epitopes on hCG mapped by monoclonal antibodies in women immunized with an anti-hCG vaccine and its implications for bioneutralization.

Title:

Antibody response against epitopes on hCG mapped by monoclonal antibodies in women immunized with an anti-hCG vaccine and its implications for bioneutralization.

Dataset

identifier:	1768655
description:	epitope description:CPTMTRVLQGVLPALPQVVC antigen name:Choriogonadotropin subunit beta host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7513023

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011181
landingPage:	http://www.iedb.org/assay/1768655

Publication

type:	Literature
publicationVenue:	J Reprod Immunol
dates:	1993

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	U S Deshmukh R Pal G P Talwar S K Gupta

Data Type

method:	ELISA

Study

name:	Antibody response against epitopes on hCG mapped by monoclonal antibodies in women immunized with an anti-hCG vaccine and its implications for bioneutralization.
description:	The epitope sequence was from the cited reference: Stevens, V.C. et al. 1986. Immunol. Lett. 12, 11-18. [PMID: 2420713]. The epitope specific mAb 357-2 inhibited binding of human antibodies to HCG by 22% and 28% in the case of 2 of 18 patients. However, the authors consider these insignificant due to the lack of direct binding.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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