Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients.

Title:

Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients.

identifier:	1768936
description:	epitope description:SSISSEDILAVLQRDDVRQYLRQYLMGP antigen name:Collagen alpha-1(XVII) chain host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	14962097

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Giovanni Di Zenzo Fabiana Grosso Michela Terracina Feliciana Mariotti Ornella De Pità Katsushi Owaribe Alessandro Mastrogiacomo Francesco Sera Luca Borradori Giovanna Zambruno

method:	western blot

name:	Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients.
description:	This epitope, initially selected by immunopanning of a phage-displayed library of random fragments of human BP180 with one or more sera from bullous pemphigoid (BP) patients, was tested in plaque dot-blot with 57 BP patients, 64 normal healthy individuals (NHI) and 17 pemphigus controls. This epitope was recognized with significantly higher frequency by BP sera than by NHI control sera. It was not recognized by pemphigus controls.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.