Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII heavy chain.

Title:

Dataset

identifier:	1770388
description:	epitope description:TDSEMDVVRFDDDNS antigen name:Coagulation factor VIII host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	2839543

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017113
landingPage:	http://www.iedb.org/assay/1770388

Publication

type:	Literature
publicationVenue:	J Clin Invest
dates:	1988

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	P A Foster C A Fulcher R A Houghten S de Graaf Mahoney T S Zimmerman

Data Type

method:	antigen inhibition

Study

name:	Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII heavy chain.
description:	The epitope inhibited binding of the antibody to factor VIII.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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