| Title: | A monoclonal antibody to factor VIII inhibits von Willebrand factor binding and thrombin cleavage. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1017123 |
| landingPage: |
http://www.iedb.org/assay/1770550 |
| type: |
Literature
|
| publicationVenue: |
Blood
|
| dates: |
1991
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
J W Precup
B C Kline
D N Fass
|
| method: |
antigen inhibition
|
| name: |
A monoclonal antibody to factor VIII inhibits von Willebrand factor binding and thrombin cleavage.
|
| description: |
Binding of the epitope specific monoclonal antibody to FVIII was inhibited by pre-incubation with the epitope. Residue D8 was found to be critical for binding by glycine substitution.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |