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identifier: 1770550
description:
epitope description:KEDFDIYDEDE
antigen name:Coagulation factor VIII
host organism:Mus musculus
antibody name:60B
aggregation:
instance of dataset
availability:
available
primaryPublications: 1902121
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017123
landingPage: http://www.iedb.org/assay/1770550
type:
Literature
publicationVenue:
Blood
dates:
1991
study type: b cell assays
subject species: Homo sapiens
fullName:
J W Precup
B C Kline
D N Fass
method:
antigen inhibition
name:
A monoclonal antibody to factor VIII inhibits von Willebrand factor binding and thrombin cleavage.
description:
Binding of the epitope specific monoclonal antibody to FVIII was inhibited by pre-incubation with the epitope. Residue D8 was found to be critical for binding by glycine substitution.