Identification of novel peptide antagonists for von Willebrand factor binding to the platelet glycoprotein Ib receptor from a phage epitope library.

Title:

Identification of novel peptide antagonists for von Willebrand factor binding to the platelet glycoprotein Ib receptor from a phage epitope library.

Dataset

identifier:	1770558
description:	epitope description:CQEPGGLVVPPTDAP antigen name:von Willebrand factor host organism:Mus musculus BALB/c antibody name:RG46
aggregation:	instance of dataset
availability:	available
primaryPublications:	7537918

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019614
landingPage:	http://www.iedb.org/assay/1770558

Publication

type:	Literature
publicationVenue:	Thromb Haemost
dates:	1995

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	V South G H Searfoss S French C Cheadle E Murray R Howk M Jaye G A Ricca

Data Type

method:	antigen inhibition (~ IC50)

Study

name:	Identification of novel peptide antagonists for von Willebrand factor binding to the platelet glycoprotein Ib receptor from a phage epitope library.
description:	Binding of the epitope specific monoclonal antibody to von Willebrand Factor was inhibited by the analog peptide. The monoclonal antibody also bound the peptide in a phage display assay.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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