The possible contribution of anti-Gal to Graves' disease. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

The possible contribution of anti-Gal to Graves' disease.

Dataset

identifier:	1770562
description:	epitope description:alpha-D-galactosyl-(1->3)-D-galactose host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	16356086

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017352
landingPage:	http://www.iedb.org/assay/1770562

Publication

type:	Literature
publicationVenue:	Thyroid
dates:	2005

Dimension

study type:	b cell assays
subject species:	Bacteria

Person

fullName:	Joseph Fullmer Arnold Lindall Rebecca Bahn Cary N Mariash

Data Type

method:	ELISA

Study

name:	The possible contribution of anti-Gal to Graves' disease.
description:	Patients with untreated Graves' disease and without Graves' ophthalmopathy had a significantly lower level of anti-Gal IgG antibodies that reacted with mouse laminin compared to healthy volunteers. A difference was not noted for patients with established Graves' ophthalmopathy who were previously treated for hyperthyroidism. There was no correlation between anti-Gal IgG and free T4, but there was a trend toward a negative correlation between total anti-Gal IgG and thyroid stimulating immunoglobulins.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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