| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1014197 |
| landingPage: |
http://www.iedb.org/assay/1770895 |
| type: |
Literature
|
| publicationVenue: |
Autoimmunity
|
| dates: |
2009
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Isabel Gonç
alves
Pierre Cherfan
Ingrid Sö
derberg
Gunilla Nordin Fredrikson
Lena Jonasson
|
| method: |
ELISA
|
| name: |
Effects of simvastatin on circulating autoantibodies to oxidized LDL antigens: relation with immune stimulation markers.
|
| description: |
The epitope sequence was cited in Fredrikson et al. Arterioscler Thromb Vasc Biol. 2003 May 1
23(5):872-8. Epub 2003 Mar 20 [PMID:12649091].
No difference was seen in IgG and IgM levels in simvastatin treated and untreated individuals. IgM response was overall higher than IgG response. A malondialdehyde (MDA)-modified epitope was used as antigen. Serum from healthy donors recognized the peptides from autoantigens.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |