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Title: Definition of Brucella A and M epitopes by monoclonal typing reagents and synthetic oligosaccharides.
identifier: 1771376
description:
epitope description:Brucella sp. O-PS M-antigen
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:Bm3-8
aggregation:
instance of dataset
availability:
available
primaryPublications: 2474505
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001218
landingPage: http://www.iedb.org/assay/1771376
type:
Literature
publicationVenue:
Infect Immun
dates:
1989
study type: b cell assays
subject species: Brucella melitensis bv. 1 str. 16M
fullName:
D R Bundle
J W Cherwonogrodzky
M A Gidney
P J Meikle
M B Perry
method:
ELISA
name:
Definition of Brucella A and M epitopes by monoclonal typing reagents and synthetic oligosaccharides.
description:
The M antigen is a homopolymer of 4,6-dideoxy-4-formamido-alpha-D-mannopyranose residues, where the repeating unit contains one alpha1,3-linked and four alpha1,2-linked monosaccharide residues.
Only one out of three epitope-specific mAbs recognized Y. enterocolitica LPS in direct ELISA, and with significantly lower titer than B. melitensis LPS.

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