Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1771893 |
| description: |
epitope description:alpha-L-Fucp-(1->3)-[alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)]-D-GlcpNAc
antigen name:Peroxidase C1A
host organism:Oryctolagus cuniculus
antibody name:Anti-glycan sera.
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
9621106 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1005199 |
| landingPage: |
http://www.iedb.org/assay/1771893 |
| type: |
Literature
|
| publicationVenue: |
Glycobiology
|
| dates: |
1998
|
| study type: | b cell assays |
| subject species: | Armoracia rusticana |
| fullName: |
I B Wilson
J E Harthill
N P Mullin
D A Ashford
F Altmann
|
| method: |
antigen inhibition (~ IC50)
|
| name: |
Core alpha1,3-fucose is a key part of the epitope recognized by antibodies reacting against plant N-linked oligosaccharides and is present in a wide variety of plant extracts.
|
| description: |
This structure represents the N-linked glycan of several plant glycoproteins such as HRP, Sophora japonica agglutinin and zucchini ascorbate oxidase.
The epitope inhibited the binding of the antibodies to horseradish peroxidase in ELISA. This reactivity, and that to other glycans, allowed Fucose residue, and less importantly, the Xylose and Mannose residues, to be assigned as requirements for the recogntion by the antisera.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
