Detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients by using synthetic hinge peptide and glycopeptide probes.

Title:

Detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients by using synthetic hinge peptide and glycopeptide probes.

Dataset

identifier:	1772008
description:	epitope description:VPSTPPTPSPSTPPTPSPS antigen name:Immunoglobulin host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	14996305

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017441
landingPage:	http://www.iedb.org/assay/1772008

Publication

type:	Literature
publicationVenue:	Nephrology (Carlton)
dates:	2004

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Ikuko Nakamura Hitoo Iwase Kenji Arai Yoko Nagai Kazunori Toma Tadashi Katsumata Yoshiyuki Hiki Tohru Kokubo Takashi Sano Yutaka Kobayashi

Data Type

method:	ELISA

Study

name:	Detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients by using synthetic hinge peptide and glycopeptide probes.
description:	Highest binding was observed against the non-glycosylated peptide. IgG binding was significantly higher in nephropathy patients than in healthy control.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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