Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells.

Title:

Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells.

identifier:	1772010
description:	epitope description:LLNVPKNMQVSIVCKILADHVTFNN antigen name:Potassium-transporting ATPase subunit beta host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	15128782

study type:	b cell assays
subject species:	Mus musculus

fullName:	Karen L Laurie Nicole L La Gruta Norbert Koch Ian R van Driel Paul A Gleeson

method:	immuno staining

name:	Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells.
description:	The epitope sequence is from the cited reference: De Silva et al. (1999) Immunology 96:145 [PMID: 10233689]. The anti-peptide antibodies recognized the epitope from extracts of dendritic cells, thymus and spleen from epitope-transgenic mice. Antibody binding was also observed by Western blotting.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.