HLA class II influences the immune response and antibody diversification to Ro60/Sjögren's syndrome-A: heightened antibody responses and epitope spreading in mice expressing HLA-DR molecules.

Title:

HLA class II influences the immune response and antibody diversification to Ro60/Sjögren's syndrome-A: heightened antibody responses and epitope spreading in mice expressing HLA-DR molecules.

Dataset

identifier:	1772461
description:	epitope description:GMALALAVTKYKQRNGWSHKDLLRL antigen name:60 kDa SS-A/Ro ribonucleoprotein host organism:Mus musculus HLA-DQ6 Tg
aggregation:	instance of dataset
availability:	available
primaryPublications:	12023392

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006957
landingPage:	http://www.iedb.org/assay/1772461

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2002

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Tawatchai Paisansinsup Umesh S Deshmukh Vaidehi R Chowdhary Harvinder S Luthra Shu Man Fu Chella S David

Data Type

method:	ELISA

Study

name:	HLA class II influences the immune response and antibody diversification to Ro60/Sjögren's syndrome-A: heightened antibody responses and epitope spreading in mice expressing HLA-DR molecules.
description:	Similar results were observed in DQ6 and DQ8 transgenic mice.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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