Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome.

Title:

Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome.

Dataset

identifier:	1772330
description:	epitope description:KRTVPPGECFIQFLSEPTITFGTAI antigen name:Muscarinic acetylcholine receptor M3 host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	15030576

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017439
landingPage:	http://www.iedb.org/assay/1772330

Publication

type:	Literature
publicationVenue:	Scand J Immunol
dates:	2004

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	D Cavill S A Waterman T P Gordon

Data Type

method:	biological activity

Study

name:	Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome.
description:	The anti-peptide antiserum inhibited carbachol-evoked colon contraction.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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