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identifier: 1772942
description:
epitope description:GSSFLSPEHQ + MCM(S3)
antigen name:Appetite-regulating hormone
host organism:Rattus norvegicus Wistar
aggregation:
instance of dataset
availability:
available
primaryPublications: 16891413
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1011666
landingPage: http://www.iedb.org/assay/1772942
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2006
study type: b cell assays
subject species: Rattus norvegicus
fullName:
Eric P Zorrilla
Shinichi Iwasaki
Jason A Moss
Jason Chang
Jonathan Otsuji
Koki Inoue
Michael M Meijler
Kim D Janda
method:
ELISA
name:
Vaccination against weight gain.
description:
The epitope has a posttranslational modification of octanoylation on Ser 3.
The antibody reacted to the n-octanoylated ghrelin, the active circulating form, while not potently binding to the the inactive, des-octanoyl form of ghrelin.