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Title: Complementary peptides against the major epitope in the NC16A domain of BP180 show no specificity as vaccines to bullous pemphigoid.
identifier: 1773121
description:
epitope description:SSYDGIPLSYLSYL
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 10527376
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017542
landingPage: http://www.iedb.org/assay/1773121
type:
Literature
publicationVenue:
J Dermatol Sci
dates:
1999
study type: b cell assays
subject species:
fullName:
Z Nie
D R Garrod
L S Chan
T Hashimoto
method:
antigen inhibition
name:
Complementary peptides against the major epitope in the NC16A domain of BP180 show no specificity as vaccines to bullous pemphigoid.
description:
The epitope sequence was complementary peptide (read 3' to 5') of RSILPYGDSMDRIE using the antisense approach.
The epitope was not able to inhibit the binding of the patient sera to human normal skin measured by immunofluorescence, or to the natural peptide RSILPYGDSMDRIE or fusion protein BP180NC16A containing the extracellular non-collagenous domain of BP180, measured by western blot.

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