Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Very low-dose tolerance with nucleosomal peptides controls lupus and induces potent regulatory T cell subsets.
identifier: 1776142
description:
epitope description:TYTEHAKRKTVTAMDVVYALKRQG
antigen name:Histone H4
host organism:Mus musculus SNF1
aggregation:
instance of dataset
availability:
available
primaryPublications: 15749855
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016114
landingPage: http://www.iedb.org/assay/1776142
type:
Literature
publicationVenue:
J Immunol
dates:
2005
study type: b cell assays
subject species: Mus musculus
fullName:
Hee-Kap Kang
Marissa A Michaels
Beate R Berner
Syamal K Datta
method:
in vivo assay
name:
Very low-dose tolerance with nucleosomal peptides controls lupus and induces potent regulatory T cell subsets.
description:
The low-dose of the epitope postponed lupus nephritis and prolonged life span. Epitope treatment reduced glomerular lesions and IgG deposites in the kidney and reduced the level of autoantibodies to dsDNA, ssDNA, histone and nucleosomes.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston