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identifier: 1775488
description:
epitope description:ELYRQKVEPLRAELQE
antigen name:Apolipoprotein A-I
host organism:Mus musculus BALB/c
antibody name:Mab-16
aggregation:
instance of dataset
availability:
available
primaryPublications: 7515687
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017624
landingPage: http://www.iedb.org/assay/1775488
type:
Literature
publicationVenue:
Biochemistry
dates:
1994
study type: b cell assays
subject species: Homo sapiens
fullName:
P E Fielding
M Kawano
A L Catapano
A Zoppo
S Marcovina
C J Fielding
method:
western blot
name:
Unique epitope of apolipoprotein A-I expressed in pre-beta-1 high-density lipoprotein and its role in the catalyzed efflux of cellular cholesterol.
description:
The epitope-specific mAb recognized pre-ß-1 HDL as shown by removal of pre-ß-1 HDL from plasma by the mAb in the gel during electrophoresis. Incubation of plasma with this mAb also significantly inhibited the efflux of labeled cholesterol from cultured fibroblast monolayers. However, the mAb did not complex apo A-I from alpha-HDL in plasma.

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