Epitope specificity of neutralizing antibodies against IFN-beta. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Epitope specificity of neutralizing antibodies against IFN-beta.

Dataset

identifier:	1775674
description:	epitope description:MSYNLLGFLQRS antigen name:Interferon beta host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	15153311

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1018326
landingPage:	http://www.iedb.org/assay/1775674

Publication

type:	Literature
publicationVenue:	J Interferon Cytokine Res
dates:	2004

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Claudia Gneiss Markus Reindl Thomas Berger Andreas Lutterotti Rainer Ehling Robert Egg Florian Deisenhammer

Data Type

method:	ELISA

Study

name:	Epitope specificity of neutralizing antibodies against IFN-beta.
description:	The epitope was manufactured with an extra GSGS spacer sequence at the C-terminus. Neutralizing Ab binding to the epitope was more pronounced in IFN-ß1a-treated patients than in IFN-ß1b-treated patients.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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