Atomic-level mapping of antibody epitopes on a GPCR. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Atomic-level mapping of antibody epitopes on a GPCR.

Dataset

identifier:	1777619
description:	epitope description:I36, F38, K43, E44, W62 antigen name:C-C chemokine receptor type 5 host organism:Mus musculus antibody name:45533
aggregation:	instance of dataset
availability:	available
primaryPublications:	19453194

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1015044
landingPage:	http://www.iedb.org/assay/1777619

Publication

type:	Literature
publicationVenue:	J Am Chem Soc
dates:	2009

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Cheryl Paes Jada Ingalls Karan Kampani Chidananda Sulli Esha Kakkar Meredith Murray Valery Kotelnikov Tiffani A Greene Joseph B Rucker Benjamin J Doranz

Data Type

method:	immuno staining

Study

name:	Atomic-level mapping of antibody epitopes on a GPCR.
description:	Epitope mapping for the mAb was performed with an arrayed library of mutations covering nearly all the amino acids in CCR5 to identify amino acid changes that resulted in loss of mAb reactivity.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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