Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1017104 |
| landingPage: |
http://www.iedb.org/assay/1781269 |
| type: |
Literature
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| publicationVenue: |
Mol Immunol
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| dates: |
2007
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Mario Di Giambattista
Theo Branckaert
Vincent Hougardy
Geoffrey Kemball-Cook
Ruth Laub
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| method: |
western blot
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| name: |
In silico prediction of FVIII epitopes recognised by natural autoantibodies in polyvalent immunoglobulin concentrates.
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| description: |
The epitope sequence is from the cited reference, Vehar et al. Nature 312, 337&ndash
342 (1984) [PMID 6438527].
The anti-epitope Igs were purified by affinity chromatography to the epitope, and the mono-specific IgG (composed mostly of IgG2) fraction was tested in Western blot against factor VIII treated or not with thrombin, showing that the A2 domain was recognized by this fraction.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
