Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.

Title:

Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.

identifier:	1781688
description:	epitope description:S139 antigen name:Hemagglutinin host organism:Homo sapiens antibody name:2B12
aggregation:	instance of dataset
availability:	available
primaryPublications:	20042511

study type:	b cell assays
subject species:	H1N1 subtype

fullName:	Jens C Krause Terrence M Tumpey Chelsey J Huffman Patricia A McGraw Melissa B Pearce Tshidi Tsibane Rong Hai Christopher F Basler James E Crowe Jr

method:	biological activity

name:	Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.
description:	The critical residue for antibody binding was mapped based on antibody escape mutants. The epitope-specific mAb was found to neutralize both 1918 and Mexico/4108/2009 viruses.

name:	iedb
homePage:	http://www.iedb.org

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