Immunological Data Discovery Index
Advanced Search
identifier: 1778648
description:
epitope description:QEGPEYWDRNT
antigen name:HLA class I histocompatibility antigen, B-7 alpha chain
host organism:Mus musculus BALB/c
antibody name:HC-10
aggregation:
instance of dataset
availability:
available
primaryPublications: 12902494
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017608
landingPage: http://www.iedb.org/assay/1778648
type:
Literature
publicationVenue:
J Immunol
dates:
2003
study type: b cell assays
subject species: Homo sapiens
fullName:
Federico Perosa
Grazia Luccarelli
Marcella Prete
Elvira Favoino
Soldano Ferrone
Franco Dammacco
method:
antigen inhibition
name:
Beta 2-microglobulin-free HLA class I heavy chain epitope mimicry by monoclonal antibody HC-10-specific peptide.
description:
The epitope competed for binding against itself, purified HLA-B7, and human T lymphoid CEM cells expressing HLA-B7. The epitope was also bound directly. Mutation of residues P3, D7, R8, and N9 reduced the response.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.