Fine epitope mapping of monoclonal antibodies to the NH2-terminal part of von Willebrand factor (vWF) by using recombinant and synthetic peptides: interest for the localization of the factor VIII binding domain.

Title:

Dataset

identifier:	1779479
description:	epitope description:MVRHENRCVA antigen name:von Willebrand factor host organism:Mus musculus BALB/c antibody name:MoAb 32B12
aggregation:	instance of dataset
availability:	available
primaryPublications:	7524613

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017932
landingPage:	http://www.iedb.org/assay/1779479

Publication

type:	Literature
publicationVenue:	Br J Haematol
dates:	1994

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	S Jorieux C Gaucher G Pié tu G Ché rel D Meyer C Mazurier

Data Type

method:	phage display

Study

name:	Fine epitope mapping of monoclonal antibodies to the NH2-terminal part of von Willebrand factor (vWF) by using recombinant and synthetic peptides: interest for the localization of the factor VIII binding domain.
description:	The epitope sequence was previously published from the cited reference Titani et al., Biochemistry. 1986 Jun 3 25(11):3171-84 [PMID: 3524673]. The epitope was deduced from overlapping peptide studies. The epitope-specific mAb bound to the phage fragment clone from a phage display library covering vWF.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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