Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.

Title:

Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.

Dataset

identifier:	1778959
description:	epitope description:LPPGLHVFPLASNRS host organism:Mus musculus antibody name:6B4
aggregation:	instance of dataset
availability:	available
primaryPublications:	11468163

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1010020
landingPage:	http://www.iedb.org/assay/1778959

Publication

type:	Literature
publicationVenue:	Blood
dates:	2001

Dimension

study type:	b cell assays
subject species:

Person

fullName:	N Cauwenberghs K Vanhoorelbeke S Vauterin D F Westra G Romo E G Huizinga J A Lopez M C Berndt J Harsfalvi H Deckmyn

Data Type

method:	flow cytometry

Study

name:	Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.
description:	The epitope specific mAb recognized the fragment of human glycoprotein Ib (GPIb) 201 to 282 by FACS screening the canine-human chimeras.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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