Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019791 |
| landingPage: |
http://www.iedb.org/assay/1779742 |
| type: |
Literature
|
| publicationVenue: |
Immunol Cell Biol
|
| dates: |
2010
|
| study type: | b cell assays |
| subject species: | Influenza A virus |
| fullName: |
David Pejoski
Weiguang Zeng
Steven Rockman
Lorena E Brown
David C Jackson
|
| method: |
in vivo assay
|
| name: |
A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody.
|
| description: |
The epitope is a S-[2,3-bis(palmitoyloxy)propyl]cysteine (Pam2Cys)-containing lipopeptides. Epitope immunization significantly reduced influenza virus load in the airways of mice after challenge. Immunization of mice with a non-lipidated longer peptide fragment M2e(2-24) in CFA/IFA induced a weaker protection.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |