Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43.

Title:

Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43.

Dataset

identifier:	1779780
description:	epitope description:cardiolipin host organism:Homo sapiens Caucasian antibody name:APS patient sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	17195232

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016188
landingPage:	http://www.iedb.org/assay/1779780

Publication

type:	Literature
publicationVenue:	Arthritis Rheum
dates:	2007

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Yiannis Ioannou Charis Pericleous Ian Giles David S Latchman David A Isenberg Anisur Rahman

Data Type

method:	ELISA

Study

name:	Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43.
description:	Serum samples from healthy control subjects showed very low binding to the epitope and to beta2-glycoprotein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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