Immunological Data Discovery Index
Advanced Search
identifier: 1780000
description:
epitope description:DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
antigen name:Amyloid beta A4 protein
host organism:Homo sapiens
antibody name:IvIg
aggregation:
instance of dataset
availability:
available
primaryPublications: 19840873
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019898
landingPage: http://www.iedb.org/assay/1780000
type:
Literature
publicationVenue:
Int Immunopharmacol
dates:
2010
study type: b cell assays
subject species: Homo sapiens
fullName:
Andrea C Klaver
John M Finke
Jyothi Digambaranath
Mamtha Balasubramaniam
David A Loeffler
method:
ELISA
name:
Antibody concentrations to Abeta1-42 monomer and soluble oligomers in untreated and antibody-antigen-dissociated intravenous immunoglobulin preparations.
description:
Antibodies to the epitope (both oligomeric and monomeric) were detected in the intravenous immunoglobulin (IvIg) preparations, although there were differences among the 3 brands tested. Antibody levels were higher when the IvIg preparations were pre-treated to dissociate antigen-antibody complexes. Specific binding to A beta 1-42 oligomers was somewhat higher than to A beta 1-42 monomers.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.