Mapping of human autoantibody binding sites on the calcium-sensing receptor. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Mapping of human autoantibody binding sites on the calcium-sensing receptor.

Dataset

identifier:	1781919
description:	epitope description:HFGVAAKDQDLKSRPESVECIRYNFRGFR antigen name:Extracellular calcium-sensing receptor host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	19580466

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019917
landingPage:	http://www.iedb.org/assay/1781919

Publication

type:	Literature
publicationVenue:	J Bone Miner Res
dates:	2010

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	E Helen Kemp Nikos G Gavalas Samia Akhtar Kai J E Krohn J Carl Pallais Edward M Brown Philip F Watson Anthony P Weetman

Data Type

method:	ELISA

Study

name:	Mapping of human autoantibody binding sites on the calcium-sensing receptor.
description:	The epitope-sequence expressing phage was initially enriched by a serum sample from the single patient with autoimmune hypocalciuric hypercalcemia (AHH). Twelve patients also reacted in ELISA when a synthetic peptide corresponding to the identified epitope sequence was used. Serum samples of the AHH patient were also positive.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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