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Title: Analysis of the epitope and neutralizing capacity of human monoclonal antibodies induced by hepatitis B vaccine.
identifier: 1782400
description:
epitope description:CTKPSDGNCT
antigen name:Large envelope protein
host organism:Homo sapiens
antibody name:HB1434, HB1440, HB1442, HB1444, HB1453, HB1460, HBV2.23
aggregation:
instance of dataset
availability:
available
primaryPublications: 20412816
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019757
landingPage: http://www.iedb.org/assay/1782400
type:
Literature
publicationVenue:
Antiviral Res
dates:
2010
study type: b cell assays
subject species: Hepatitis B virus subtype adr
fullName:
Kazuto Tajiri
Tatsuhiko Ozawa
Aishun Jin
Yoshiharu Tokimitsu
Masami Minemura
Hiroyuki Kishi
Toshiro Sugiyama
Atsushi Muraguchi
method:
biological activity
name:
Analysis of the epitope and neutralizing capacity of human monoclonal antibodies induced by hepatitis B vaccine.
description:
The peptide was cyclic by a disulphide bond between residues C1 and C9.
HBV-neutralizing capacity was investigated using the HepaRG cell line that has been established as an in vitro HBV infection model. Epitope specific mAbs of IgG1 or IgG2 subclass showed the same results.

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