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identifier: 1782426
description:
epitope description:CTKPSDGNCT
antigen name:Large envelope protein
host organism:Homo sapiens
antibody name:HB1434, HB1440, HB1442, HB1444, HB1453, HB1460, HBV2.23, HB1465, HBV2.18
aggregation:
instance of dataset
availability:
available
primaryPublications: 20412816
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019757
landingPage: http://www.iedb.org/assay/1782426
type:
Literature
publicationVenue:
Antiviral Res
dates:
2010
study type: b cell assays
subject species: Hepatitis B virus subtype adr
fullName:
Kazuto Tajiri
Tatsuhiko Ozawa
Aishun Jin
Yoshiharu Tokimitsu
Masami Minemura
Hiroyuki Kishi
Toshiro Sugiyama
Atsushi Muraguchi
method:
surface plasmon resonance (SPR)
name:
Analysis of the epitope and neutralizing capacity of human monoclonal antibodies induced by hepatitis B vaccine.
description:
The peptide was cyclic by a disulphide bond between residues C1 and C9.
Epitope specific mAbs of IgG1 or IgG2 subclass and with kappa or lambda light chain showed similar results. The mAbs showed KD values for small HBsAG in the range of 1.22-803 nM.

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