Use of molecular simulation for mapping conformational CYP2E1 epitopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Use of molecular simulation for mapping conformational CYP2E1 epitopes.

Dataset

identifier:	1782738
description:	epitope description:K243, E244, E248, K251 antigen name:Cytochrome P450 2E1 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	15456790

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017201
landingPage:	http://www.iedb.org/assay/1782738

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	2004

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Matteo Vidali Mats Hidestrand Erik Eliasson Elisa Mottaran Emanuela Reale Roberta Rolla Giuseppa Occhino Emanuele Albano Magnus Ingelman-Sundberg

Data Type

method:	immunoprecipitation

Study

name:	Use of molecular simulation for mapping conformational CYP2E1 epitopes.
description:	Site-directed mutagenesis of the epitopic residue(s) caused a reduction in antibody recognition in 1 of 5 sera.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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