Presence of heterogeneous thyroid-stimulating antibodies in sera from individual Graves' patients as shown by synthesized thyrotropin receptor peptide application: evidence showing two independent epitopes and a possible recognition of two epitopic regions by one antibody molecule.

Title:

Dataset

identifier:	1784256
description:	epitope description:VFFEEQEDEIIGFG antigen name:Thyrotropin receptor host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7581943

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020692
landingPage:	http://www.iedb.org/assay/1784256

Publication

type:	Literature
publicationVenue:	Eur J Endocrinol
dates:	1995

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	H Sugawa T Akamizu S Kosugi Y Ueda C Ohta J Okuda

Data Type

method:	antigen inhibition

Study

name:	Presence of heterogeneous thyroid-stimulating antibodies in sera from individual Graves' patients as shown by synthesized thyrotropin receptor peptide application: evidence showing two independent epitopes and a possible recognition of two epitopic regions by one antibody molecule.
description:	The epitope effectively inhibited the specific binding of purified TSH-R stimulating autoantibody (TSH-R-Sab) Ig to FRTL-5 cell lysates.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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