A defined epitope on the human choriogonadotropin alpha-subunit interacts with the second extracellular loop of the transmembrane domain of the lutropin/choriogonadotropin receptor.

Title:

A defined epitope on the human choriogonadotropin alpha-subunit interacts with the second extracellular loop of the transmembrane domain of the lutropin/choriogonadotropin receptor.

Dataset

identifier:	1784944
description:	epitope description:GVSSYMKVSICLPMDVE antigen name:Lutropin-choriogonadotropic hormone receptor host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	8917465

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1009625
landingPage:	http://www.iedb.org/assay/1784944

Publication

type:	Literature
publicationVenue:	Eur J Biochem
dates:	1996

Dimension

study type:	b cell assays
subject species:	Sus scrofa

Person

fullName:	L Couture J J Remy H Rabesona F Troalen E Pajot-Augy V Bozon T Haertle J M Bidart R Salesse

Data Type

method:	biological activity

Study

name:	A defined epitope on the human choriogonadotropin alpha-subunit interacts with the second extracellular loop of the transmembrane domain of the lutropin/choriogonadotropin receptor.
description:	The anti-epitope antiserum was inefficient in decreasing hormone binding, but it displayed a significant capacity to inhibit CG-induced cAMP production. The effect of the epitope-specific antiserum on CHO-93 cells expressing full-length LH/CG receptor was measured. Binding was determined by addition of 125I-labeled human CG.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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