Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1785168 |
| description: |
epitope description:H33, G34, Y38, R39, W80, W81, R91, L93, T107, N111, K114, K115, S118, D119, G120, N121
antigen name:Gal d 4
host organism:Mus musculus BALB/c
antibody name:HyHEL-10 Fv mutant LN92D
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
20038580 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019576 |
| landingPage: |
http://www.iedb.org/assay/1785168 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2010
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| study type: | b cell assays |
| subject species: | Gallus gallus |
| fullName: |
Akiko Yokota
Kouhei Tsumoto
Mitsunori Shiroishi
Takeshi Nakanishi
Hidemasa Kondo
Izumi Kumagai
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| method: |
calorimetry
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| name: |
Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme.
|
| description: |
The interaction of epitope-specific HyHEL-10 Fv mutant LD92N with hen egg-white lysozyme (HEL) was analyzed by isothermal titration calorimetry, performed at four temperatures (25, 30, 35 and 40ºC). The mutation resulted in a small decrease in the binding constant compared to wild type HyHEL-10 Fv (KA = 8210 1/nM).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
