Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1785183 |
| description: |
epitope description:H33, G34, N37, Y38, R39, W80, W81, R91, L93, N95, T107, N111, K114, K115, I116, S118, D119, G120
antigen name:Gal d 4
host organism:Mus musculus BALB/c
antibody name:HyHEL-10 Fv mutant HY53A
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| aggregation: |
instance of dataset
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| availability: |
available
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| primaryPublications: |
17166830 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019578 |
| landingPage: |
http://www.iedb.org/assay/1785183 |
| type: |
Literature
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| publicationVenue: |
J Biol Chem
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| dates: |
2007
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| study type: | b cell assays |
| subject species: | Gallus gallus |
| fullName: |
Mitsunori Shiroishi
Kouhei Tsumoto
Yoshikazu Tanaka
Akiko Yokota
Takeshi Nakanishi
Hidemasa Kondo
Izumi Kumagai
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| method: |
calorimetry
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| name: |
Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL.
|
| description: |
The interaction of epitope-specific HyHEL-10 Fv mutant HY53A with hen egg-white lysozyme (HEL) was analyzed by isothermal titration calorimetry, performed at four temperatures (25, 30, 35, and 40 C). The value is reported for 30 C at pH 7.2. The mutation resulted in a decrease in the binding constant compared to wild type HyHEL-10 Fv (KA = 4200 1/nM).
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
