| identifier: | 1785527 |
| description: |
epitope description:E7, F8, E9, P312, V313, D314, L315, S316, K317, V318, T319, S320, K321, C322, G323, S324, L325, G326, N327, I328, H329, H330, K331, P332, G333, G334, G335, Q336, V337, E338, V339, K340, S341, E342, K343, L344
antigen name:Other Homo sapiens (human) protein
host organism:Mus musculus
antibody name:Alz-50
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
15721985 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1014424 |
| landingPage: |
http://www.iedb.org/assay/1785527 |
| type: |
Literature
|
| publicationVenue: |
Free Radic Biol Med
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Quan Liu
Mark A Smith
Jesus Avilá
John DeBernardis
Mayank Kansal
Atsushi Takeda
Xiongwei Zhu
Akihiko Nunomura
Kazuhiro Honda
Paula I Moreira
Catarina R Oliveira
Maria S Santos
Shun Shimohama
Gjumrakch Aliev
Jack de la Torre
Hossein A Ghanbari
Sandra L Siedlak
Peggy L R Harris
Lawrence M Sayre
George Perry
|
| method: |
western blot
|
| name: |
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
|
| description: |
The epitope sequence was previously described in Goedert et al, Neuron:3(519) 1989 [PMID:2484340].
The epitope-specific mAb only bound to tau after oxidation with HNE. The mAb also stained brain samples from a patient with Alzheimer Disease.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |