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Title: IgG subclass and light chain distribution of anticardiolipin and anti-DNA antibodies in systemic lupus erythematosus.
identifier: 1785548
description:
epitope description:cardiolipin
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 3129997
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016328
landingPage: http://www.iedb.org/assay/1785548
type:
Literature
publicationVenue:
Ann Rheum Dis
dates:
1988
study type: b cell assays
subject species: Homo sapiens
fullName:
A E Gharavi
E N Harris
M D Lockshin
G R Hughes
K B Elkon
method:
ELISA
name:
IgG subclass and light chain distribution of anticardiolipin and anti-DNA antibodies in systemic lupus erythematosus.
description:
Clinical complications were found slightly more frequently in SLE patients with sera containing the non- or weak-complement fixing subclasses (IgG2 and IgG4) of epitope-specific Ab than in patients with sera containing complement fixing (IgGl and IgG3) subclasses. Light chain analysis showed a trend towards use of lambda chains for the epitope-specific Ab in the SLE sera.

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